Research / Unapproved

Ecnoglutide: Research Status and Trial Overview

Molecular formulaC194H304N48O61
Molecular weight4285 g/mol
Registered trials15
PubChem CID162625103

What Ecnoglutide Is

Ecnoglutide is a large synthetic peptide compound (molecular formula C194H304N48O61) identified in chemical databases under PubChem CID 162625103. It has no FDA-approved label, and no brand name, indication, or mechanism description is available from regulatory sources. It is currently classified as an unapproved research compound, meaning it has not been reviewed or authorized by the FDA for any use in patients.

Trial Footprint

Ecnoglutide has been registered in 15 clinical trials to date. Several of these are studying the compound, sometimes listed under related names such as XW003 or VRB-101, in people with obesity or overweight and associated conditions.

Sampled trials include a study evaluating ecnoglutide injection in obese participants with knee osteoarthritis, a study of the compound in obese participants with obstructive sleep apnea who are also receiving positive airway pressure therapy, and a study assessing weekly oral dosing for weight maintenance among participants with obesity or overweight and weight-related comorbidities. These trials remain in active stages, with recruitment or ongoing participant follow-up underway.

FAQ

Is ecnoglutide FDA-approved?
No. Ecnoglutide is currently classified as an unapproved research compound with no FDA-approved label, brand name, or indication. Any use outside of registered clinical trials is not supported by regulatory approval.
What conditions is ecnoglutide being studied for?
Based on registered trials, ecnoglutide is being studied in people with obesity or overweight, including those with related conditions such as knee osteoarthritis and obstructive sleep apnea. These studies are ongoing and do not establish proven benefit.
How many clinical trials involve ecnoglutide?
Ecnoglutide appears in 15 registered clinical trials as of the most recent data. Some of these trials refer to the compound under alternate names, including XW003 and VRB-101.
Are there other names for ecnoglutide?
Yes. Trial records show the compound has also been referenced as XW003 and VRB-101 in different study registrations, though ecnoglutide is the primary compound name used here.
What is ecnoglutide's chemical identity?
Ecnoglutide is a large peptide with the molecular formula C194H304N48O61, cataloged under PubChem CID 162625103. Detailed mechanism of action information is not available in the absence of an approved label.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-09-26