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Research / Unapproved

MOTS-c: Research Status and Trial Overview

Molecular formulaC101H152N28O22S2
Molecular weight2174.6 g/mol
Registered trials9
PubChem CID146675088

What MOTS-c Is

MOTS-c is a mitochondrial-derived peptide studied in early clinical and laboratory research. It does not have an FDA-approved label, and no approved indications, dosing, or brand names exist for it. Its chemical identity is catalogued under PubChem CID 146675088. At this time, MOTS-c should be understood strictly as a research compound rather than a therapeutic product.

Trial Footprint

Public trial registries list 9 registered studies referencing MOTS-c. The sample of available studies includes a completed trial on exercise following breast cancer diagnosis (NCT04013568), an active but not recruiting cohort study on deafness-gene screening (NCT06133946), and a recruiting study on long-term outcomes after vestibular implantation (NCT06500975). These titles suggest MOTS-c appears across a range of unrelated research contexts rather than a single defined development program. The presence of a study in a registry does not indicate that MOTS-c was proven safe or effective for any use.

FAQ

Is MOTS-c FDA-approved?
No. MOTS-c has no FDA-approved label, indications, or brand names. It is currently studied only as a research compound.
What is MOTS-c used for?
There is no approved use for MOTS-c. It appears in a small number of registered clinical studies covering varied topics, but this does not establish any confirmed use.
How many clinical trials involve MOTS-c?
Public registries currently list 9 registered studies referencing MOTS-c, spanning different research areas rather than one focused program.
Are there known side effects of MOTS-c?
No adverse event report data is currently available for MOTS-c, so no side effect pattern can be summarized at this time.
What kind of compound is MOTS-c?
MOTS-c is a peptide identified in chemical databases by its PubChem CID. It has a defined molecular structure but no approved pharmaceutical status.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: ClinicalTrials.gov PubChem

Updated 2026-09-26