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Tesofensine: Research Status and Trial Data

Molecular formulaC17H23Cl2NO
Molecular weight328.3 g/mol
Registered trials13
PubChem CID11370864

What tesofensine is

Tesofensine is an investigational chemical compound (PubChem CID 11370864) with the molecular formula C17H23Cl2NO. It does not have an approved drug label from regulatory authorities, and no brand name or indication has been authorized. Any information about tesofensine reflects its status as a research compound rather than a marketed medicine.

Trial footprint

Tesofensine has been studied across 13 registered clinical trials. Available records include a placebo-controlled study in Parkinson patients with motor fluctuations that tested multiple oral doses over 14 weeks, which was completed. Other registered work includes a study pairing tesofensine with metoprolol in subjects with type 2 diabetes mellitus, also completed, and a withdrawn study evaluating a tesofensine-containing combination in hypothalamic obesity. These records describe study design and status only, not established safety or effectiveness.

FAQ

Is tesofensine an approved medication?
No. Tesofensine has no approved regulatory label, brand name, or authorized indication. It remains an investigational compound studied in clinical trials.
What has tesofensine been studied for?
Registered trials have examined tesofensine in contexts including Parkinson patients with motor fluctuations, type 2 diabetes mellitus in combination with metoprolol, and hypothalamic obesity as part of a combination product. These are study registrations and do not confirm efficacy.
How many clinical trials involve tesofensine?
There are 13 registered clinical trials involving tesofensine, spanning different study designs and statuses, including completed and withdrawn trials.
What is tesofensine chemically?
Tesofensine is a chemical compound with the molecular formula C17H23Cl2NO and a molecular weight of about 328.3. It is catalogued in PubChem under CID 11370864.
Are there known side effects of tesofensine?
No adverse event report data was available for tesofensine in the reviewed dataset. Because it lacks an approved label, no official safety profile has been established.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: PubChem ClinicalTrials.gov

Updated 2026-09-26